Group Sequential Design Class for Clinical Trials

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Documentation for package ‘seqmon’ version 2.5

• DESCRIPTION file.

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seqmon-package	seqmon
alphaspend	Function that calculates the upper boundaries for efficacy
alphaspendf	The default alpha spending function
betaspend	Function that calculates the lower boundaries for futility
betaspendf	The default beta spending function
calcBoundaries	Function for calculating the efficacy and futility boundaries
calcBoundaries-method	Class '"sequential.design"'
curtail	Generic function that calculates the probability to declare efficacy at the end of study given the Z value at the current look
curtailDesign	Function for calculating the probability for efficacy given known information
curtailDesign-method	Class '"sequential.design"'
getProbabilities	Function that calculates the cumulative probabilities to declare efficacy and futility
getProbabilities-method	Class '"sequential.design"'
plotBoundaries	Function that plots the efficacy and futility boundaries
plotBoundaries-method	Class '"sequential.design"'
print-method	Class '"sequential.design"'
printDesign	Function that displays the features of the design
printDesign-method	Function that displays the features of the design
seqmon	Generic function that calculates boundary crossing probabilities used for monitoring clinical trials
sequential.design	The sequential design class
sequential.design,sequential.design-class	Class '"sequential.design"'
sequential.design-class	Class '"sequential.design"'
setAlphaspendfString	Function that Sets the expression of the base alpha spending function as a string
setAlphaspendfString-method	Class '"sequential.design"'
setBaseAlphaspendf	Function that sets the base alpha spending function
setBaseAlphaspendf-method	Class '"sequential.design"'
setBaseBetaspendf	Function that sets the base beta spending function
setBaseBetaspendf-method	Class '"sequential.design"'
setBetaspendfString	Function that sets the expression of the base beta spending function as a string
setBetaspendfString-method	Class '"sequential.design"'
setCurrentLook	Function that sets the current look number
setCurrentLook-method	Class '"sequential.design"'
setDatestamp	Function that sets the date stamp of the design object
setDatestamp-method	Class '"sequential.design"'
setNoncentrality	Function that sets the noncentrality parameter
setNoncentrality-method	Class '"sequential.design"'
setTimes	Function that sets the look times
setTimes-method	Class '"sequential.design"'
summary-method	Class '"sequential.design"'
summaryDesign	Function that shows the cumulative probabilities for efficacy and futility
summaryDesign-method	Function that shows the cumulative probabilities for efficacy and futility
updateDesign	Function that updates the design
updateDesign-method	Class '"sequential.design"'