Flexible and Efficient Evaluation of Principal Surrogates/Treatment Effect Modifiers

Documentation for package ‘pssmooth’ version 1.0.3

bootRiskCurve	Bootstrap Estimation of Conditional Clinical Endpoint Risk under Placebo and Treatment Given Biomarker Response to Treatment in a Baseline Surrogate Measure Three-Phase Sampling Design
plotMCEPcurve	Plotting of the Estimated Marginal Causal Effect Predictiveness Curve
riskCurve	Estimation of Conditional Clinical Endpoint Risk under Placebo and Treatment Given Biomarker Response to Treatment in a Baseline Surrogate Measure Three-Phase Sampling Design
summary.riskCurve	Summary of Point and Interval Estimation of a Marginal Causal Effect Predictiveness Curve
testConstancy	Testing of the Null Hypotheses of a Flat and a Constant Marginal Causal Effect Predictiveness Curve
testEquality	Testing of the Null Hypothesis of Equal Marginal Causal Effect Predictiveness Curves for Two Biomarkers, Endpoints, or Baseline Covariate Subgroups