Seamless Adaptive Multi-Arm Multi-Stage Enrichment

Documentation for package ‘SAME’ version 0.1.0

conduct.phase2	Function to identify the most promising treatment-biomarker-linked subgroup
conduct.phase3	Function to estimate the hazard ratios and other statistics of the selected subgroup
example.1	A Time-to-event dataset containing the time and other attributes of 643 patients.
example.2	A Time-to-event dataset containing the time and other attributes of 643 patients.
find.cutoffs	Function to calibrate the cutoff points under null hypothesis
sim.trial	Function to simulate Bayesian seamless multi-arm biomarker-enriched phase II/III designs
sim.trial.2	Function to simulate Bayesian seamless multi-arm biomarker-enriched phase II/III designs with user-defined cutoff points